Cyno TACI HEK293
CBP74694
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| I. Background | |
| 食蟹猴（Cyno）的TACI（由TNFRSF13B基因编码）是TNF受体超家族成员，主要表达于B细胞和活化T细胞表面。它顺利获得结合APRIL和BAFF/BLyS，促进T细胞非依赖性抗体应答和浆细胞分化，同时负向调节BAFF驱动的B细胞过度活化，在体液免疫稳态中扮演关键角色。该基因的突变与普通变异型免疫缺陷病（CVID） 和IgA缺陷相关。 | |
| II. Description | |
| Cyno TACI HEK293细胞，在 HEK293细胞的基础上，稳定表达 Cyno TACI。 | |
| III. Introduction | |
| Expressed gene: | Cyno TACI |
| Host Cell: | HEK293 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM + 10% FBS + 2 μg/ml Puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| IV. Representative Data | |
 Figure 1. Recombinant Cyno TACI HEK293 constitutively expressing Cyno TACI. |
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